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KMID : 0386520160250010145
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Research Institute of Korean Medicone
2016 Volume.25 No. 1 p.145 ~ p.153
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The Experimental Study of Glycyrrhiza uralensis on Wound Healing by Antioxidant Effect
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Lee Yun-Kyung
Roh Seok-Seon
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Abstract
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Objectives : The purpose of this study is to evaluate the wound healing potential of Glycyrrhiza uralensis extract.
Methods : Free radical scavenging activity tests for DPPH, peroxynitrite (ONOO) and hydroxyl radical (·OH) and total phenolic contents of Glycyrrhiza uralensis extract were conducted. Tube formation assay was performed using human umbilical vein endothelial cells (HUVECs).
Results : The results showed that Glycyrrhiza uralensis extract exerted inhibitory effects on ONOO and ·OH. Tube formation in HUVEC was increase in a dose dependent manner.
Conclusions : These results show the potential to promote the wound healing process by Glycyrrhiza uralensis extract.
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KEYWORD
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Glycyrrhiza uralensis , wound healing , ONOO , tube formation
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